MCD Inc.

Malaria Control and Elimination

Background

Medical Care Development International has been working to reduce and eventually eliminate the burden of malaria for almost 40 years. In 2015, there were 212 million new cases of malaria and 429,000 deaths. MCDI's work in prevention through vector control, intermittent preventive therapy in pregnancy, malaria vaccines, malaria diagnostics, case management, monitoring, evaluation and surveillance has helped to significantly reduce the burden of malaria in populations served by MCDI-supported work.


Prevention: Integrated Vector Control

MCDI is a leading expert in integrated vector control, with experience in various malaria-endemic countries through multiple intervention methods. MCDI's integrated vector control work has helped to significantly reduce the prevalence of malaria infection and incidence of malaria cases in beneficiary populations by dramatically suppressing transmission through reductions in vector abundance, infectivity, and human blood-feeding contact.


MCDI has substantial operational experience and technical expertise in planning, managing, monitoring and evaluating the following vector control strategies: (1) mass top-up distribution and hang-up campaigns for Long Lasting Insecticide Treated Nets (LLINs); (2) keep-up of LLINs through antenatal care and school-based distribution; (3) Indoor Residual Spraying (IRS); and, (4) Larval Source Management (LSM).


Read more about our extensive vector control experience.


Prevention: Intermittent Preventive Therapy in Pregnancy

MCDI works to improve the provision of Intermittent Preventative Treatment in pregnancy (IPTp) as part of antenatal care services in several countries MCDI has programs. Most recently, MCDI provided extensive support to the National Malaria Control Programs and Ministries of Health in Benin and Equatorial Guinea to strengthen and increase coverage of IPTp. MCDI trains health workers in providing IPTp and conducted health situation analyses on IPTp coverage in order to improve antenatal care. MCDI has worked with governments to provide IPTp in public health facilities since 2005.


Learn more about MCDI's experience in preventing malaria in pregnancy.


Prevention: Vaccines

MCDI has been a core implementing partner of the Equatorial Guinea Malaria Vaccine Initiative (EGMVI), conducting clinical trials of Sanaria Inc.'s whole sporozoite Plasmodium falciparum malaria vaccine candidate (PfSPZ). Sanaria's objective is to develop a PfSPZ vaccine that confers at least 80% protective efficacy for at least 6 months. The EGMVI's goal is to provide clinical evidence of the safety, tolerability and efficacy of the PfSPZ vaccine in subjects residing in Equatorial Guinea as a basis for bringing the PfSPZ vaccine to licensure and eventual use in conjunction with standard malaria control interventions to eliminate malaria on Bioko Island and other endemic settings.


Read more about EGMVI


Diagnosis

MCDI has assumed a technical leadership role in malaria diagnostics internationally. MCDI has helped the World Health Organization in setting global standards for diagnostics, and is a key innovator in developing, testing and deploying systems to train and provide supportive supervision to laboratory and clinical staff on proper diagnosis of malaria. In addition to providing technical and operational support to various countries through bilateral agreements, MCDI was the prime contractor under the USAID-PMI centrally funded Improving Malaria Diagnostics (IMaD) project from 2007-2012, and was the lead technical sub-contractor for malaria diagnostics under the follow-on MalariaCare project (2013-2017), with MCDI operating in 12 countries. MCDI was recently selected as the lead technical sub-contractor for malaria diagnostics and co-lead for case management for the PSI-led IMPACT Malaria project (2018-2022), which will operate in a total of 28 countries.


Read more about MCDI's experience in diagnosis


Case Management

Under various bilateral agreements, MCDI supported national malaria control programs and national health systems in providing quality treatment of malaria, both in the public and private health sectors. Training on case management of uncomplicated and severe malaria as well as malaria in pregnancy has been an essential component of MCDI's projects. MCDI also assists in developing training courses to improve the quality of case management systems.


Learn more about treatment methods


Monitoring, Evaluation and Surveillance

According to independent international experts, MCDI established, in Equatorial Guinea, one of the most comprehensive and robust malaria information monitoring systems in existence today. Since 2004, MCDI has led the efforts to develop and implement PDA and later tablet-based data collection tools to collect, process, analyze, disseminate and act upon data from annual malaria indicator surveys, from passive case reporting through the National Health Information System (established and operated with MCDI's support), from active case reporting through focused screening and treatment interventions, from IRS, LLIN and LSM data management systems, and from sentinel-site based entomological monitoring. MCDI's entomological monitoring systems include measuring vector abundance by species, infectivity, target site and metabolic resistance to insecticides, and behavioral resistance.


Read more about our monitoring, evaluation and control experience.


Supply Chain Management

MCDI has extensive experience in supply chain management for malaria control acquired through various means. MCDI adheres to international best-practice and standards for the procurement and management of malaria supplies. MCDI specializes in international procurement and the use of customized software and mHealth applications to quantify supply requirements, order, manage and track the distribution and consumption of supplies.


Learn more about our supply chain management systems


Elimination

MCDI's goal is to help eliminate malaria from endemic settings and ultimately to help eradicate malaria globally. In this regard, MCDI supports the development of standard operating procedures, policies and guidelines for elimination. MCDI's elimination-related strategies include data analysis to deploy stratified and targeted interventions that respond most cost-effectively to local transmission contexts, and the deployment of mass screening and treatment campaigns.


Read about our elimination strategies